The Sanctuary Sun Boat III’s luxury Nile cruises depart from either Luxor or Aswan (downstream from Aswan to Luxor or upstream from Luxor to Aswan).
In Luxor the dock is in front of Karnak Temple, beside the floating police station while in Aswan the dock is found in the new corniche beside the Aswan New Bridge. We recommend flying from Cairo to either destination. The flying time from Cairo to Luxor is 1 hour, and from Cairo to Aswan it is 1 hour 30 minutes. Driving to and from Luxor or Aswan is not usually recommended as it would require a police escort and the driving time is both long and tiring - approximately 12 hours from Cairo to Luxor, and 15 hours from Cairo to Aswan.